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Besamux 100 200

Besamux 200mg

Registration No: VD-13141-10
Compositions: Acetylcystein: 200mg.
Shape: Powdered medicine to take orally
Packing: Box contains 30 sachets
Drug class: Respiratory Group
Indications: Used dilutes the respiratory tract, in the circumstances specified disorders of the respiratory secretion.
Manufacturer  : Éloge France VietNam
Distributor: HYPO CO.,LTD

Product Description

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Compositions:

Acetylcystein: 200 mg

Lactose, Aspartam, orange flavoring agent, Sunset yellow, PEG 6000 q.s for 1 sachet

Indications:

Besamux is used to dilute respiratory mucus, and is prescribed for cases of respiratory mucus disorder:

  • Sinusitis, pharyngitis
  • Acute and chronic bronchitis
  • Clear the respiratory system in case of opening windpipe

Contraindications:

  • Children under 2 years old
  • Urinary phenylketonuria
  • Oversensitive to acetylcystein

Adverse Drug Reactions (ADR) and how to deal with them:

  • Acetylcystein has a wide safe range. Even though it is rare to see clear clinical bronchospasm due to acetylcystein, it can still happens for medicine containing acetylcystein.
  • Usual (ADR > 1/100): nausea, vomiting
  • Unusual (1/1000 < ADR < 1/100): sleepy, headache, tinnitus. Stomatitis, prolonged runny nose. Rash, urticaria.
  • Rare (ADR < 1/1000): bronchospasm alongside systemic anaphylaxis reactions. Fever, ague

Treatment for ADR:

  • Use diluted acetylcystein solution can decrease the probability of vomiting due to the medicine
  • Treat systemic anaphylaxis reactions immediately by injecting under the skin adrenalin (0.3 – 0.5 ml of 1/1000 solution), breath 100% oxygen, set up endotracheal if needed, inject IV fluids to increase serum volume, inhale beta – adrenalin in case of bronchospasm, inject into veins 500 mg hydrocortisone or 125 mg methylprednisolone.

Usage:

  • Children from 2 to 7 years old: 1 sachet/time, 2 times/day
  • Adult and children over 7: 1 sachets/time, 3 times/day
  • Mix medicine with half a glass of water

Notice during use:

  • Coughing is a basic mechanism to protect lungs and therefore should be understood
  • Be careful for patients with stomach or duodenal ulcers.
  • Patients with asthma or history of allergy

Use in Pregnancy or lactating women

  • During pregnancy: research on animals shown that the medicine does not cause teratogenic. However, these data should not be extrapolated on humans
  • During breastfeeding: avoid using this medicine due to lack of research

Effects of drug on driving or use machines:

  • None recorded

Overdose and how to treat:

  • Acetylcystein overdose happens when injection occurs to fast and with too high a dose

+ Symptoms: similar to symptoms of anaphylaxis, but more severe, especially the drop in blood pressure. Others include: respiratory failure, blood depletion, intravascular scattered coagulations, kidney failure

  • Treatment: treating the symptoms

Pharmacology:

  • This medicine reduces the viscosity of respiratory system mucus by splitting the disulfua connection in mucoprotein and makes it easier to eject sputum through coughing or mechanical means

Pharmacokinetics:

  • After taking, acetylcystein is quickly absorbed in the digestive system and got its acetyl reduced by liver to turn into cysteine.
  • The medicine reaches peak in serum after about 0.5 – 1 hour after taking. Kidney clearance rate takes up 30% of clearance rate in the whole body

Shelf-life: 36 months from production date

Do not use beyond the date on packaging

Storage:  Keep in a dry place, at temperature not above 30oC, protect from light.

Specification: Standard of manufacturer

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